New research indicates that patients who discontinue popular slimming jabs like Mounjaro or Wegovy may regain shed pounds far faster than those who end traditional lifestyle plans.
Published data in a major health publication points out that while overweight individuals often shed about a fifth of their total mass while using the jabs, the weight comes back at an estimated rate of nearly a kilo each month upon discontinuation.
"Individuals purchasing such drugs must be informed of the potential of fast rebound weight gain when the treatment concludes," stated expert Dr. Susan Jebb.
Such speed of regain implies a reversion to pre-treatment weight in about a year and a half.
Analyzing Approaches
The analysis, which examined dozens of studies involving thousands of participants, contrasted the results of the injectable medications with conventional dieting.
Researchers emphasize that people who shed pounds through diet and exercise generally experience a slower weight regain—approximately 100 grams monthly—post-intervention.
The Reason for the Quick Rebound
Experts believe the mechanism of the jabs accounts for the amplified regain.
GLP-1 drugs imitate a natural hormone called GLP-1, which moderates feelings of fullness.
"Sustained high doses of GLP-1 concentrations far above than normal might result in the system to generate a reduced amount of its own natural GLP-1, and could lessen sensitivity to its actions," explained Dr. Adam Collins, a nutrition specialist.
"Discontinuation of this hormone supplement means hunger is uncontrolled, making excessive eating much more probable."
A Chronic Disease?
Health authorities advise the jabs for people with weight-linked health risks, alongside recommended lifestyle changes.
Many experts argue that, considering the significant potential of weight regain, the treatment should be considered life-long.
This perspective is echoed by drug manufacturers, who note that the results "emphasize the chronic character of obesity," comparing it to managing conditions like diabetes.
Patient Testimonies
Users who have stopped the jabs report a sudden return of hunger.
"I experienced a switch activating and you're instantly extremely hungry," described a patient.
This difficulty is compounded if users have not developed permanent lifestyle or habit changes during treatment.
Growing Use
Figures indicate that millions of people in the UK have used weight-loss jabs in the last 12 months, with demand remaining high.
- Adoption is greater among females compared to men.
- The 40s and 50s demographic shows the greatest level of interest.
- A large proportion obtain the medications through private prescriptions rather than public health services.
Ultimately, experts caution that while GLP-1 drugs are potent tools for shedding pounds, they are not a permanent cure and lasting health benefits hinges on combined behavioural changes.
